Figure 2.
Unc119 genes and proteins. A, Structure of Unc119 genes and gene products. Mutations associated with disease are noted in the UNC119A protein. Blue bars denote approximate positions of SH2- and SH3-interacting domains. B, Sequence alignment of UNC119 paralogs and PrBP/δ. Conserved residues are shown white-on-black background, conservative substitutions white-on-grey background.