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. 2012 Nov;14(11):1015–1022. doi: 10.1593/neo.12870

Figure 2.

Figure 2

RPTP-β regulates Met tyrosine 1356 phosphorylation in HNSCC cells. (A) UMSCC-22B metastatic HNSCC tumor cells were infected with empty adenovirus or RPTP-β-expressing adenovirus. (B) UMSCC-22A primary HNSCC tumor cells were infected with NT or RPTP-β-targeting shRNA lentivirus. Forty-eight hours post-infection, cells were treated with vehicle (-) or HGF (10 ng/ml, +) for 30 minutes. Equal amounts of whole-cell lysates were analyzed by Western blot probed with indicated antibodies. Immunoreactive bands were quantified by chemifluorescence using a STORM Image analyzer. Data are means ± SEM, N = 3; *P < .05. Inset shows representative Western blots.