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. 2012 Nov 16;109(46):788–794. doi: 10.3238/arztebl.2012.0788

Table 2. Process variables relating to ancillary diagnosis and antipsychotic pharmacotherapy (with indication of subgroup size)*1.

Ward A passive dissemination Ward B active dissemination
pre post pre post
Head CT on initial presentation 100% 100% 75% 86%
(2 pts.) (2 pts.) (8 pts.) (7 pts.)
Pregnancy test for women up to age 50 33% 50% 78% 100%*2
(6 pts.) (8 pts.) (9 pts.) (8 pts.)
ECG monitoring for all 34 days 24 days 33 days 29 days
Drug monitoring on Day 35 33% 38% 15% 69%*2
Monotherapy on Day 35 71% 55% 39% 50%
Underdosing on Day 35 29% 50% 15% 7%*2
Overdosing on Day 35 0% 8% 23% 14%
Mean dose on Day 35 545 CPZ 500 CPZ 608 CPZ 594 CPZ
Mean dose for patients with initial presentation 886 CPZ*2 450 CPZ 467 CPZ 423 CPZ
(2 pts.) (2 pts.) (8 pts.) (7 pts.)

*1he DGPPN guidelines recommend a head CT on the initial presentation of schizophrenia and regular ECG monitoring (at least at the start of treatment and 4 weeks after); according to the PORT recommendations, the daily antipsychotic dose should lie between 300 und 1000 chlorpromazine equivalents (CPZ) (or up to 500 CPZ for initial presentations).

*2≈ statistically significant at 5%.