Table 2.
PMN and PMN-elastase cause dyshesion, loss of E-cadherin expression, and downmodulation of keratin in cancer cells.
| n = 3 | T3M4 | HuH7 | ||
|---|---|---|---|---|
| Cultivated with | PMN | PMN elastase | PMN | PMN elastase |
| Dyshesion* | 47,19% (±2,30) | 38,86% (±7,33) | 37,05% (±1,91) | 46,33% (±3,84) |
| E-cadherin expression** | 53,81 (±20,22) | 78,76% (±19,64) | 22,61% (±5,55) | 54,12% (±23,04) |
| Keratin expression | 36,78% (±20,13) | 31,85% (±20,18) | 17,57% (±9,56) | 37,20% (±28,77) |
*Measured as area devoid of cells in relation (%) of the total cell area.
**Measured as mean fluorescence intensity (MFI) in relation to the MFI of untreated cells which were set as 100 %.