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. 2012 Oct 3;4(11):1176–1187. doi: 10.1093/gbe/evs081

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Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution 2012.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc/3.0/), which permits non-commercial reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. 5.— — Distribution of ORFan and non-ORFan genes among genomes of Escherichia coli strains. (A) The average number of E. coli stains per protein cluster in the ORFan and non-ORFan cluster groups; (B) the frequency distribution of number of E. coli stains per cluster used in the ORFan and non-ORFan comparison groups (this excludes ORFan clusters with only one member, which is the most common size of a cluster). ORFans typically have narrow distributions, while non-ORFans in the t2 comparison group are present in most genomes. Non-ORFans in the t1 group have an intermediate distribution. The letters in (A) denote significantly different results by the Wilcoxon test (results from Student’s t-test are the same).