Table 4.

Effects of Amino Acid Replacements on SP1 Zinc Finger 2 (zf2) Structure

Peptidea	Human zf2 (-13M)b	M-13V peptidec
M-13V	0.135	0
M-13I	0.091	0.174
T-11S	0.048	0.131
S-9M	0	0.135
S-9V	0.045	0.130
Y-8F	0	0.135
S-9L	0	0.135
T-11S/S-9L	0.039	0.137
S-9V/Y-8F	0.045	0.130
T-11S/S-9M	0.039	0.137
T-11S/Y-8F	0.039	0.137

^aLowest free energy peptide structures are labeled according to amino acid replacements relative to the human zf2 peptide.

^bRMSD values of each peptide compared with the lowest free energy human zf2 structure.

^cRMSD values compared with the M-13V peptide.