Table 6.
Intervention group (n=61) | Control group (n=107) | Mean Difference (95% CI) | Standard Error | t-statistic | P value | |
---|---|---|---|---|---|---|
Conditional Estimates | ||||||
Duration of ART | ||||||
MPR if ART ≥995 days (n) | 97% (31) | 98% (53) | −1.1% (−2.5, 2.3) | 0.01 | −0.11 | 0.91 |
MPR if ART <995 days (n) | 98% (37) | 84% (53) | 14.5% (6.3, 22.7) | 0.04 | 3.46 | <0.01 |
MPR if ART ≥154 days (n) | 98% (61) | 89% (107) | 9.5% (4.9, 14) | 0.02 | 4.06 | <0.01 |
MPR if ART ≥230 days (n) | 99% (60) | 88% (103) | 10.7% (6.3, 15) | 0.02 | 4.71 | <0.01 |
MPR if ART ≥231 days (n)* | 99% (60) | 98% (101) | 0.6% (−2.1, 3) | 0.01 | 0.42 | 0.67 |
MPR if ART ≥250 days (n) | 99% (59) | 98% (98) | 0.05% (−1.2, 2) | 0.009 | 0.06 | 0.95 |
Baseline BMI, kg/m2 | ||||||
MPR if BMI is <18.5 (n) | 99% (12) | 66% (15) | 33.3% (10.8, 55.9) | 0.12 | 2.9 | <0.01 |
MPR if BMI is ≥18.5 (n) | 98.35% (45) | 98.32% (92) | 0.03% (−0.019, 0.02) | 0.01 | 0.03 | 0.98 |
Baseline Stage of Disease | ||||||
MPR if HIV disease stage I or II (n) | 99% (31) | 98% (68) | 0.8% (−2.6, 4.1) | 0.02 | 0.45 | 0.65 |
MPR if HIV disease stage III or IV (n) | 99% (15) | 78% (19) | 20.9% (−2.8, 44.6) | 0.12 | 1.73 | 0.09 |
Baseline CD4 count,, mean cells/μl | ||||||
MPR if CD4+lymphocyte count ≤350 (n) | 99% (24) | 80% (44) | 18.9% (10.8, 27.0) | 0.04 | 4.57 | <0.01 |
MPR if CD4+ lymphocyte count >350 (n) | 98% (44) | 94% (63) | 4.8% (1.8, 7.7) | 0.02 | 3.19 | <0.01 |
Abbreviations: ART, antiretroviral therapy; BMI, body mass index; MPR, medication possession ratio. Total N for matching is 175 reduced to 168 observations after imposing common support (7 treated cases not on support). Overall estimates, N=61 (intervention), 107 (control).
Difference in MPR between arms was no longer significant when participants with 231 days of ART or greater were included in the analysis.