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. Author manuscript; available in PMC: 2012 Dec 5.
Published in final edited form as: Transl Neurosci. 2010 Sep;1(3):188–194. doi: 10.2478/v10134-010-0023-x

Figure 3.

Figure 3

Effect of HFS on α- and β-secretase activity in hippocampal slices of TgCRND8 mice. Values of the α-secretase activity (A) and β-secretase activity (B) are expressed as percentages compared to their own non-stimulated slices normalized to 100%. Each graph shows the mean ± S.E.M. The data were analyzed using a Two-way ANOVA in a within-subjects design, followed by Bonferroni’s post-hoc tests for pair-wise comparisons. Significant difference was designated as ***p<0.001. The results show that HFS stimulation was associated with selective enhancement in α, but not β-secretase activity in the CA1 region of the hippocampus.