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. Author manuscript; available in PMC: 2013 Dec 1.
Published in final edited form as: Lancet Neurol. 2012 Nov 6;11(12):10.1016/S1474-4422(12)70227-2. doi: 10.1016/S1474-4422(12)70227-2

Figure 1. Florbetapir (18F) binding in members of the Colombian kindred by age group and clinical diagnosis.

Figure 1

Sagittal and axial standard uptake value ratio maps are presented in standardised atlas space. Cortical amyloid-β is evident in all patients with mild cognitive impairment and dementia and in all PSEN1 E280A mutation carriers aged 30 years or older. There is variability of visible tracer binding within each age subdivision and within the mild cognitive impairment and dementia groups. Typical patterns of non-specific white matter binding occurred in carriers under age 30 years and in all non-carriers. Participants’ data are displayed in age groupings to help protect individual anonymity.