Table 2.
Regions of interest (ROI) analysis of fractional anisotropy (FA) and Evans index for three groups of patients
ROI | Control | INPH | PD | ANOVA | Tukey’s post-hoc |
---|---|---|---|---|---|
Anterior thalamic radiation |
0.426 ± 0.010 |
0.318 ± 0.010 |
0.417 ± 0.007 |
<0.0001 |
INPH < control = PD |
Forceps minor |
0.466 ± 0.011 |
0.375 ± 0.011 |
0.461 ± 0.008 |
<0.0001 |
INPH < control = PD |
Superior longitudinal fasciculus |
0.514 ± 0.020 |
0.421 ± 0.020 |
0.505 ± 0.015 |
0.0020 |
INPH < control = PD |
Corticospinal tract |
0.646 ± 0.009 |
0.608 ± 0.009 |
0.643 ± 0.006 |
0.0040 |
INPH < control = PD |
Forceps major |
0.762 ± 0.025 |
0.673 ± 0.025 |
0.750 ± 0.018 |
0.0252 |
INPH < control = PD |
Evans index | 0.28 ± 0.02 | 0.38 ± 0.04 | 0.29 ± 0.03 | <0.0001 | INPH > control = PD |
INPH, idiopathic normal pressure hydrocephalus; PD, Parkinson’s disease; ANOVA, one-way analysis of variance;
Data represent mean ± SD (standard deviation). INPH < control = PD, significant FA reductions in INPH compared to control and PD, INPH > control = PD, significant Evans index elevation in INPH compared to control and PD.