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. 2012 Oct 26;68(Pt 11):1279–1283. doi: 10.1107/S1744309112037736

Figure 1.

Figure 1

Schematic outline of the roles of G3PDH and GDH in metabolism. The cytosolic G3PDH (blue) interconverts glycerol 3-phosphate and dihydroxyacetone phosphate depending on the catabolic/anabolic state of the cell. The membrane-bound G3PDH (red) preferentially oxidizes glycerol 3-phosphate and transfers the electrons to ubiquinone in the respiratory electron-transport chain for ATP production. GDHs (green) preferentially oxidize glycerol to dihydroxyacetone. Both glycerol and dihydroxyacetone can be phosphorylated at the expense of ATP by glycerol kinase (GK) and dihydroxyacetone kinase (DHAK), respectively.