Table 6.

Factors associated with improvement of fatigue

Variable	Full modela			Reduced model
ESAS items	OR	p-value	95% CI	OR	p-value	95% CI
Pain	1.05	0.18	0.98 - 1.12	1.05	0.12	0.99 - 1.12
Nausea	1.03	0.51	0.95 - 1.11
Depression	1.02	0.63	0.94 - 1.11
Anxiety	0.98	0.63	0.90 - 1.07
Appetite	1.08	0.01	1.01 - 1.16	1.09	0.01	1.02 - 1.16
Drowsiness	0.95	0.12	0.88 - 1.02	0.96	0.16	0.90 - 1.02
Feeling of well-being	1.09	0.06	1.00 - 1.19	1.08	0.06	1.00 - 1.17
Shortness of breath	0.97	0.45	0.91 - 1.04
Sleep disturbance	1.00	0.93	0.93 - 1.08
Anemia	0.86	0.55	0.52 - 1.43
Low albumin	1.25	0.50	0.66 - 2.37
MDAS items
Consciousness	1.41	0.42	0.61 - 3.28
Disorientation	0.89	0.65	0.55 - 1.46
Memory change	0.78	0.24	0.52 - 1.18
Digit Span	0.71	0.27	0.38 - 1.32	0.69	0.16	0.41 - 1.17
Attention	0.55	0.07	0.28 - 1.07	0.57	0.07	0.31 - 1.05
Disorganized thinking	1.26	0.21	0.87 - 1.81
Perception distrurbance	0.68	0.23	0.35 - 1.29
Delusions	1.20	0.56	0.63 - 2.29
Psychomotor activity	1.34	0.58	0.47 - 3.86
Sleep disturbance	1.06	0.76	0.73 - 1.54
Alcoholism	0.82	0.50	0.46 – 1.46
Cancer Typesb
Breast	0.84	0.66	0.38 – 1.85
Gastrointestinal	1.07	0.80	0.63 - 1.81
Genitourinary	1.92	0.04	1.02 - 3.62	1.74	0.04	1.01 - 2.99
Gynecologic	1.19	0.65	0.56 - 2.53
Sarcoma	1.34	0.47	0.60 - 3.01
Othersc	1.17	0.60	0.65 - 2.11

ESAS: Edmonton symptom assessment scale; MDAS: Memorial delirium assessment scale;

^a- Logistic regression model.

^b- Reference: Head & Neck or Lung cancer.

^c- Unknown primary, melanoma, skin, leukemia, lymphoma, brain.