Figure 1. Evolutionary histories of known nuclear envelope components. (A) Cartoon of structures at, and associated with, the nuclear envelope. Shown are the nuclear pore complex/karyopherins (red), Sun/Kash (LINC complex) proteins (blue) and known components of a nuclear lamina (lamins, green; NUP-1, yellow). (B) The evolutionry distributions of the nuclear pore complex/karyopherins, Sun/Kash proteins and known nuclear lamina proteins are shown colorized and overlaid upon a schematic phylogeny of the eukaryotes, emphasizing the five contemporary-recognized supergroups. FECA, First eukaryotic common ancestor; LECA, Last eukaryotic common ancestor; KAP, karyopherin; SAR + CCTH, stramenopiles alveolates, and Rhizaria + cryptomonads, centrohelids, telonemids and haptophytes.