Figure 2. Relative sizes of metazoan and trypanosomatid nuclei and lamina monomers. Blue ovals indicate the relative sizes of a fibroblast and trypanosome nucleus, at 10 μm and 1.5 μm in diameter. The molecular weight of the unikont lamins is approximately 60 kDa while NUP-1 is 450 kDa; these are indicated as white bars close to the indicator lines for each nucleus. The inference is that the structural arrangement of the lamina in these systems is potentially very different.