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(A) Insulin secretion (ng/mL/h/islet) was measured in naked (light grey bars, CTR) and nano-PEG-encapsulated (dark grey bars, Nano) islet cultures cultured overnight after encapsulation stimulated with 2.8 mM, or 28 mM glucose for 24 h. (B) Insulin stimulation index of the naked and nanoparticle-coated islets shown in (A). At least 20 islets were included in each group, and the data represents 3 individual experiments.
