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. Author manuscript; available in PMC: 2013 Dec 1.
Published in final edited form as: Clin Chest Med. 2012 Dec;33(4):667–680. doi: 10.1016/j.ccm.2012.09.002

Figure 2.

Figure 2

Histopathological sections of lung biopsy, hematoxylin and eosin stain. (A) Low-power overview showing filling of alveolar spaces by eosinophilic material (magnification 310). (B) High-power view showing granular eosinophilic material and cholesterol clefts. (magnification 3200). Birefrigent particles were identified with polarizing microscopy, consistent with the presence of crystalline indium-tin oxide. (C) Periodic acid-Schiff (PAS) stain after diastase digestion, showing granular, PAS-positive intraalveolar material, and cholesterol clefts (magnification X100). from Cummings, K. Donat W. Ettensohn, David. Pulmonary Alveolar Proteinosis at an Indium Processing Facility. Am J Respir Crit Care Med. 181; 2010: 458–464, with permission).