. Author manuscript; available in PMC: 2013 Nov 20.

Published in final edited form as: Biochemistry. 2012 Nov 7;51(46):9342–9353. doi: 10.1021/bi300890y

Table 1.

Kinetic Analysis of the Genome Maturation Reactions.

[Protomer]	cos-Cleavage Reaction Rate	Strand Separation Reaction Rate	Cleavage:Separation Reaction Extent
100 nM	k_obs= 2.1 min⁻¹	k_obs= 0.25 min⁻¹	1.4
80 nM	k_obs= 1.4 min⁻¹	k_obs= 0.19 min⁻¹	1.4
40 nM	k_obs= 0.95 min⁻¹	k_obs= 0.045 min⁻¹	1.4
20 nM	k_fast= 0.69 min⁻¹ (60% total amplitude) k_slow= 0.086	k_obs= 0.033 min⁻¹	1.4