. Author manuscript; available in PMC: 2012 Dec 6.

Published in final edited form as: Aquat Toxicol. 2010 Dec 29;102(1-2):18–23. doi: 10.1016/j.aquatox.2010.12.016

Table 2.

Specific activities of the zebrafish COMT toward catecholic compounds

Substrate	Specific Activity (nmol/min/mg)^a,^b
L-DOPA	5.44 ± 0.51^#
Methyl-DOPA	0.20 ± 0.05^#
Carbidopa	2.19 ± 0.22^#
Dopamine	37.43 ± 1.07^*
Epinephrine	18.94 ± 0.96^*
Isoproterenol	41.04 ± 1.24^*
Apomorphine	0.529 ± 0.18^#
2-OH-E₁	157.33 ± 6.67^*
4-OH-E₁	46.31 ± 3.46^#
2-OH-E₂	144.57 ± 4.29^*
4-OH-E₂	85.80 ± 1.12^*
Dobutamine	128.54 ± 5.66^*

Data represent means ± S.D. derived from four experiments.

Statistical significance versus the activity of control is indicated by * with p<0.0001 or ^# with p<0.005. The sample size (n) analyzed was 8.