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. Author manuscript; available in PMC: 2014 Feb 1.
Published in final edited form as: Alcohol Clin Exp Res. 2012 Aug 30;37(2):223–233. doi: 10.1111/j.1530-0277.2012.01922.x

Table 5. Effects of Mg depletion on EtOH-related behaviors.

In B6 mice, dietary depletion of Mg significantly increased EtOH-induced LORR duration relative to control diet, but did not significantly affect EtOH-induced ataxia or EtOH-induced hypothermia (n=13–15/treatment). In S1 mice, dietary depletion of Mg did not significantly affect any measure of EtOH intoxication, but approximately 75% of S1 mice died as a result of Mg treatment (n=4–16/treatment).

B6 S1
Control diet Mg deficient diet Control diet Mg deficient diet
Ataxia 69.6 ±7.0 58.5 ±11.3 66.1 ±6.1 39.3 ±16.1
Hypothermia 2.8 ±0.3 2.5 ±0.4 3.9 ±0.2 3.7 ±0.3
LORR duration 66.9 ±10.2 * 97.4 ±9.5 179.8 ±9.8 126.0 ±35.4

Data are Means ±SEM.

*

p<.05 vs. Control diet