Table 10.
Changes in functional connectivity between three time points in antipsychotic drug treatment.
| SZ1 > SZ0 | SZ6 > SZ0 | SZ6 > SZ1 | |
|---|---|---|---|
| Medial frontal cortex to left nucleus accumbens | |||
| z-score | 1.65 | −0.78 | −2.32 |
| Significance a | 0.0495* | 0.2177 | 0.0102* |
| Medial frontal cortex to right nucleus accumbens | |||
| z-score | 0.23 | 0.75 | 0.44 |
| Significance a | 0.4090 | 0.2266 | 0.3300 |
| Medial frontal cortex to left hippocampus | |||
| z-score | −0.09 | −1.78 | −1.49 |
| Significance a | 0.4641 | 0.0375* | 0.0681 |
| Medial frontal cortex to right hippocampus | |||
| z-score | −2.56 | −2.84 | −1.00 |
| Significance a | 0.0052* | 0.0023** | 0.1587 |
| Left nucleus accumbens to left hippocampus | |||
| z-score | 0.49 | 0.98 | 0.39 |
| Significance a | 0.312 | 0.1263 | 0.348 |
| Right nucleus accumbens to right hippocampus | |||
| z-score | −0.77 | −2.08 | −1.08 |
| Significance a | 0.2207 | 0.0188* | 0.1401 |
aOne-tailed significance. *p < 0.05, **p < 0.005.
SZ0, baseline; SZ1, 1 week of antipsychotic drugs treatment; SZ6, 6 weeks of antipsychotic drug treatment.