Table 3.

Decision task condition.

Region	Hemisphere	Cluster peak coordinatesa	Pb	kE
DEC task rCBF increases following 1 week of APD treatment, SZ1 > SZ0
Putamen	L	−26, 6, −6	0.000	646
Putamen	R	30, 14, −6	0.000	132
Putamen	R	28, 6, −6	0.021	41
DEC task rCBF decreases following 1 week of APD treatment, SZ1 < SZ0
Anterior cingulate cortex	L, R	4, 10, 40	0.037	41
DEC task rCBF increases following 6 weeks of APD treatment, SZ6 > SZ0
Putamen	L	−36, −4, −4	0.000	153
Putamen	R	24, 6, −2	0.000	150
Putamen	L	−18, 14, −8	0.006	60
DEC task rCBF decreases following 6 weeks of APD treatment, SZ6 < SZ0
Medial frontal gyrus	L, R	0, 50, 18	0.011	53
DEC task rCBF increases between week 1  and week six of APD treatment, SZ6 < SZ1
Putamen	L	−26, 4, −6	0.005	55

^aMontreal Neurological Institute (MNI) anatomical coordinates in x, y, z.

^bp values FDR corrected.

SZ0, baseline; SZ1, after 1 week of antipsychotic drugs treatment; SZ6, after 6 weeks of antipsychotic drug treatment; APDs, antipsychotic drugs; R, right; L, left; kE, kernel extent in voxels; rCBF, regional cerebral blood flow.

Regional cerebral blood flow changes during decision task from baseline after 1 and 6 weeks of treatment and between 1 and 6 weeks of treatment.