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. Author manuscript; available in PMC: 2013 Dec 1.
Published in final edited form as: Curr Opin Pharmacol. 2012 Jul 21;12(6):751–759. doi: 10.1016/j.coph.2012.07.006

Figure 2. Relationship of prostatic tumor growth to serum cholesterol level in a pre-clinical model.

Figure 2

Normocholesterolemic immunodeficient mice had their serum cholesterol determined and 5 days later were implanted with subcutaneous LNCaP tumors (4 per mouse). Tumor growth and serum cholesterol were monitored until the experiment was complete (day 20). Tumor growth is plotted as tumor volume (mm3) vs. time (days) and serum cholesterol level is plotted as cholesterol concentration (mg/dL) vs. time (days) ± SEM. Note that as tumor volume increases, serum cholesterol level decreases.