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. Author manuscript; available in PMC: 2012 Dec 6.
Published in final edited form as: Med J Zambia. 2010;37(2):104–110.

Table 2.

HIV patient inclusion in sepsis studies

Treatment Study Location Diagnosis HIV & patient inclusion
Early goal-directed therapy Rivers, et al4 United States Severe sepsis Immunosuppression excluded; 3% of pts HIV+
Antibiotics < 1hr Kumar, et al5 Canada Septic shock 1.4% AIDS; 15% on immunosuppressive treatment
Albumin vs. Crystalloids SAFE6 Australia/NZ ICU pts, 18% sepsis Not excluded, number not specified
Steroids CORTICUS9 Europe and Israel Septic shock Immunosuppression excluded
Annane, et al10 France Refractory septic shock AIDS excluded
Activated Protein C PROWESS15 Worldwide Severe sepsis Excluded CD4 < 50
Goal Hb Hebert, et al11 Canada ICU pts, 6% sepsis Not excluded, number not specified
Low tidal volumes ARDSNET12 United States ARDS, 26% sepsis Not excluded, number not specified
Insulin COIITSS13 France Septic shock Not excluded, number not specified