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Association of AAG, Ape1, and MGMT activity with GBM resistance to radiation and alkylating agents: one laboratory’s experiencea.
Risk for progression following radiation and alkylator therapy was determined by Cox proportional hazards regression in dichotomous models with median activity as the cut point. See text for details
Activities in GBMs were measured by biochemical assay.
Tumors assayed for AAG and Ape1 were from the sample of 87 assayed for MGMT.
