Figure 5.

A: EMB negative for cellular and humoral rejection (grade 0R) showing mild interstitial edema suggesting mild ischemic effect (note isolated inflammatory cells without forming aggregates). B: Grade 1R revealed compact interstitial mononuclear cell aggregate without evident myocyte damage. C: This case of 2R showed a focus of myocyte damage (muscle fiber between arrows was infiltrated and damaged by mononuclear cells. D: This less compact inflammatory aggregate encased multiple degenerating cardiomyocytes (2R).