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. Author manuscript; available in PMC: 2013 Apr 1.
Published in final edited form as: Compr Physiol. 2012 Apr 1;2:1541–1584. doi: 10.1002/cphy.c110052

Figure 11.

Figure 11

Scheme of the V-type H+-ATPase. H+-ATPases use the energy released by the hydrolysis of ATP to move protons against their concentration gradients. The V0 domain is involved in translocation of the protein. The V1 domain is involved in ATP-hydrolysis. The precise subunits composition is not entirely clear and several slightly different schemes are proposed. For details see recent excellent reviews providing details about subunits and domains of V-type H+-ATPase (68, 162, 474, 635).