Table 2.
Clinical presentation of 14 HIV-infected patients with histoplasmosis and TB coinfection
| Symptoms | Number (%) | Findings | Number (%) |
|---|---|---|---|
| Weight loss | 12 (85.7) | Anemia (female < 12 g/dL, male < 13 g/dL) | 12 (85.7) |
| Asthenia | 11 (78.5) | Increased LDH (> 221 U/L) | 5/6 (83.3) |
| Fever | 9 (64.2) | Lymphadenopathy | 11 (78.5) |
| Anorexia | 8 (57.1) | Lung infiltrates* | 11 (78.5) |
| Cough | 7 (50) | Increased ALP (> 96 U/L) | 10/13 (76.9) |
| Expectoration | 6 (42.8) | Hepatomegaly† | 9/13 (69.2) |
| Abdominal pain | 6 (42.8) | Splenomegaly† | 7/13 (53.8) |
| Dyspnea | 5 (35.7) | Increased AST (> 40 U/L) | 6/13 (46.1) |
| Diaphoresis | 4 (28.5) | Leukopenia (< 4,500 cells/mL) | 6 (42.8) |
| Chest pain | 4 (28.5) | Mucocutaneous lesions | 6 (42.8) |
| Behavioral disturbances | 3 (21.4) | Increased ALT (> 40 U/L) | 5/13 (38.4) |
| Diarrhea | 3 (21.4) | Thrombocytopenia (< 150,000) | 4 (28.5) |
| Vomiting | 3 (21.4) | Lung calcifications* | 3 (21.4) |
| Headache | 2 (14.2) | Ascites† | 2/13 (15.3) |
| Lung nodules* | 1 (7.1) |
ALP = alkaline phosphatase; ALT = alanine aminotransferase; AST = aspartate aminotransferase.
*
Findings on chest X-ray.
†
Findings on abdominal ultrasound.