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. 2012 Dec 5;87(6):1094–1098. doi: 10.4269/ajtmh.2012.12-0292

Table 5.

Treatment, outcomes, and serum itraconazole levels of 12 HIV-infected patients who had histoplasmosis and TB and received itraconazole

Treatment Number (%) Itraconazole levels Outcome
Level (μg/mL) Number (%)
Quinolone and itraconazole 6* Not done 4 Successful therapy
> 1.0 1 Successful therapy
> 1.0 1 Lost to follow-up
Rifampicin and itraconazole 6 Not done 3 Successful therapy
< 0.5 1 Death
< 0.5 1 Relapse
< 0.5 1 Successful therapy
*

Three patients started with rifampicin and then changed to quinolone.