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. 2012 Sep 21;21(26):5511–5527. doi: 10.1093/hmg/dds395

Figure 9.

Figure 9.

Inhibition of myosin-II with blebbistatin reduces the percentage of microtubules with wave-like folds in growth cones of neurons depleted of DCX and DCLK. (A and B) Control growth cones treated with DMSO or blebbistatin. Treatment with blebbistatin did not significantly decrease the levels of microtubules with wave-like folds in control growth cones. (C–D) Growth cones of DCX+DCLK siRNA neurons that were treated with DMSO or blebbistatin. Treatment with blebbistatin significantly decreases the number of microtubules with wave-like folds resulting from DCX+DCLK depletion. Scale bar = 6 μm.