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. Author manuscript; available in PMC: 2013 Apr 2.
Published in final edited form as: Neuroimage. 2012 Jan 25;60(2):1587–1595. doi: 10.1016/j.neuroimage.2012.01.079

Figure 1.

Figure 1

Original and randomly shuffled BOLD signals. A: Resting-state fMRI data from dorsal anterior cingulate cortex (dACC) and right anterior insula cortex (rAI). Bandpass filtering between 0.01 and 0.1 Hz was applied. B: Surrogate data where the time indices for the two BOLD signals in Figure 1A were randomly but synchronously shuffled. Cross correlation (CC) remained the same for both Figure 1A and 1B. The reduction in total interdependence (TI) was indicative of the amount of temporal relationship between the two signals in Figure 1A not captured by CC.