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. Author manuscript; available in PMC: 2012 Dec 6.
Published in final edited form as: Biometrics. 2012 Feb 7;68(2):521–531. doi: 10.1111/j.1541-0420.2011.01708.x

Table 4.

Estimation of the joint distribution of age at diagnosis and stage at diagnosis using the proposed methods. EMP represents the empirical distribution estimate, PH represents the proposed semiparametric estimator based on proportional hazards model, and AFT represents the proposed estimator based on accelerated failure time model

Stage/Age 65–74
75–84
85+
Estimate 95% C.I. Estimate 95% C.I. Estimate 95% C.I.
Localized EMP 0.299 (0.278–0.319) 0.145 (0.130, 0.161) 0.018 (0.013, 0.025)
PH 0.222 (0.189–0.252) 0.129 (0.108–0.151) 0.027 (0.014–0.045)
AFT 0.153 (0.131–0.174) 0.101 (0.085–0.118) 0.019 (0.012–0.028)
Regional EMP 0.073 (0.061, 0.084) 0.039 (0.031, 0.047) 0.004 (0.002, 0.007)
PH 0.064 (0.049–0.079) 0.042 (0.029–0.061) 0.010 (0.002–0.026)
AFT 0.051 (0.040–0.063) 0.034 (0.024–0.044) 0.005 (0.001–0.009)
Distant EMP 0.270 (0.251, 0.289) 0.121 (0.107, 0.136) 0.030 (0.022, 0.037)
PH 0.267 (0.236–0.296) 0.176 (0.133–0.217) 0.062 (0.017–0.112)
AFT 0.353 (0.319–0.386) 0.217 (0.186–0.246) 0.066 (0.046–0.091)