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. 2012 Dec 7;18(45):6577–6586. doi: 10.3748/wjg.v18.i45.6577

Figure 4.

Figure 4

Immunohistochemical analysis and assessment of phospho Akt positivity based on molecular alterations in gastric cancer tissues. A: Gastric adenocarcinoma showing phospho Akt (pAkt) positivity. Original magnification, ×200; B: pAkt expression significantly correlates with human epidermal growth factor receptor 2 (HER2) overexpression (P < 0.01) but not with phosphatidylinositol 3-kinase, catalytic, alpha polypeptide (PIK3CA) mutations (P = 0.37) or Epstein-Barr virus (EBV) infection (P = 0.69).