Table 3.

Signature Transcripts Differentially Regulated by the Presence of Dietary Glucosinolates in Scaptomyza flava Whose Homologs are Differentially Regulated in the Same Direction by Environmental Stressors in Drosophila melanogaster and/or Those That Were Not Correlated with Development in Larvae Reared in GKO versus WT plants (developmental expression changes explain <50% of the log₂ fold change)

S. flava Assembled Transcript Region	Log2 Fold Change in Expression in S. flava Reared on WT vs. GKO Plants	D. melanogaster Homolog	FlyBase Potential Molecular Function (MF) and Biological Process (BP)	Stressors in D. melanogaster Causing Similar Changes
SF10967	Induced	Ance-3	MF, peptidyl-dipeptidase; BP, proteolysis	Age
SF777	Induced	Thor	MF, translational regulator; BP, response to starvation; immune response; determination of adult lifespan; response to oxidative stress; regulation of cell growth; triglyceride metabolic process; negative regulation of cell size; response to stress; antibacterial humoral response; regulation of mitochondrial translation	Starvation, phenobarbital, oxidative stress
SF4724	Induced	Muc68Ca	MF, unknown; BP, blood coagulation	N/A
SF2958	Induced	Gie	MF, GTP binding; BP, sister chromatid segregation	N/A
SF1034	Induced	Hml	MF, protein homodimerization; BP, hemolymph coagulation, hemostasis, wound healing	N/A
SF2502	Induced	CG7715	MF, chitin binding; BP, chitin metabolic process	N/A
SF8380	Induced	CG5830	MF, phosphatase; BP, unknown	N/A
SF8519	Induced	DnaJ-1	MF, heat shock protein binding, unfolded protein binding; BP, response to heat	N/A
SF693	Induced	Hsc70-4	MF, chaperone binding; BP:RNA interference, axon guidance, neurotransmitter secretion, embryonic development via the syncytial blastoderm, nervous system development, axonal fasciculation, vesicle-mediated transport	N/A
SF11108	Induced	Rpp20	MF, protein binding; BP, unknown	N/A
SF12295	Induced	Mur89F	MF, chitin binding; BP, chitin metabolic process	N/A
SF10011	Repressed	hoip	MF, mRNA binding; BP, nervous system development	N/A
SF2851	Repressed	shep	MF, mRNA binding; BP, gravitaxis	N/A
SF12099	Repressed	CoVa	MF, cytochrome-c oxidase, BP:positive regulation of cell cycle	Starvation, age
SF2493	Repressed	eIF3-S10	MF, translation initiation factor activity; BP, mitotic spindle elongation, mitotic spindle organization	N/A
SF3615	Repressed	CG42336	MF, unknown; BP, unknown	Starvation, age
SF271	Repressed	dod	MF, peptidyl-prolyl cis–trans isomerase; BP, epidermal growth factor receptor signaling pathway	N/A
SF13113	Repressed	CG7181	MF, cytochrome-c oxidase; BP, mitochondrial electron transport, cytochrome c to oxygen	Starvation, age
SF3948	Repressed	Cpr72Ec	MF, structural constituent of chitin-based cuticle; BP, unknown	N/A
SF1424	Repressed	CG4169	MF, ubiquinol-cytochrome-c reductase; BP, mitochondrial electron transport, ubiquinol to cytochrome c	Starvation, age
SF2735	Repressed	DNaseII	MF, deoxyribonuclease II; BP, nurse cell apoptosis	Starvation