Figure 1.

Plasma levels of (A) angiopoietin-1 and (B) angiopoietin-2 and corresponding angiopoietin-2:angiopoietin-1 ratios (C) in children in Indonesia with dengue hemorrhagic fever (DHF) (n = 26) and dengue shock syndrome (DSS) (n = 23) on day 0 (day of admission), day of discharge (n = 44) and in a control group of healthy children from Indonesia (n = 25). The minimum detection limit of angiopoietin-1 was 0.1 ng/mL. Black points indicate non-survivors. Horizontal lines represent median values. P values were determined by Wilcoxon signed-rank test for data in time and Mann-Whitney U test for comparison with the control group. *P < 0.05.