Table 1.
Day* |
|||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
sGHeV doses (μg) | AGM | −42 | −7 | 7 | 14 | 28 | −42 | −7 | 7 | 14 | 28 |
|
|
||||||||||
HeV | NiV | ||||||||||
0† | 9 | <20 | <20 | 24 | ‡ | ‡ | <20 | <20 | <20 | ‡ | ‡ |
10 | 16 | <20 | >2560 | >2560 | >2560 | 1074 | <20 | 379 | 226 | >2560 | 2147 |
17 | <20 | >2560 | >2560 | 905 | 537 | <20 | 134 | 134 | 537 | 453 | |
18 | <20 | >2560 | >2560 | 453 | 537 | <20 | 189 | 134 | 189 | 453 | |
50 | 13 | <20 | >2560 | >2560 | >2560 | 757 | <20 | 379 | 189 | 189 | 453 |
14 | <20 | 1514 | >2560 | >2560 | 537 | <20 | 28 | 47 | 226 | 134 | |
15 | <20 | 2147 | 757 | >2560 | 905 | <20 | 67 | 95 | 757 | 1074 | |
100 | 10 | <20 | >2560 | 2147 | 1810 | 453 | <20 | 67 | 113 | 268 | 453 |
11 | <20 | >2560 | >2560 | >2560 | 1514 | <20 | 134 | 189 | 905 | 1514 | |
12 | <20 | >2560 | >2560 | >2560 | 757 | <20 | 189 | 226 | >2560 | 1514 |
Day after NiV challenge.
Received adjuvant alone.
Not sampled; shading indicates increase in serum neutralization titer.