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. Author manuscript; available in PMC: 2012 Dec 6.
Published in final edited form as: Clin Pharmacol Ther. 2012 Aug 8;92(3):360–365. doi: 10.1038/clpt.2012.95

Figure 1. Performance of the DMET Plus array.

Figure 1

The Affymetrix Drug Metabolizing Enzymes and Transporters (DMET) genotyping platform scans 1,931 different variants. The accuracy of the platform was determined for SNPs that passed two quality control criteria. The first quality control filter removed any SNPs with call rates below 98%, and the second filter removed any SNPs that were not in Hardy-Weinberg equilibrium (HWE) at a P-value < 0.001. A total of 1,692 SNPs passed QC and the concordance of genotypes was determined between the DMET array and those available from orthogonal genotyping. A total of 259 SNPs were assessed by DMET and at least one additional genotyping method.