Table 2.
All DMET discordant genotypes for all SNPs with < 98% concordance between DMET and other orthogonal methods.
| Discordant Patient ID | rsID | Gene | DMET Genotype | SNPstream Genotype | SNP6/500K Genotype | Golden Gate Genotype | Concordant Methods |
|---|---|---|---|---|---|---|---|
| 1 | rs1800566 | NQO1 | C/C | C/T | C/C | C/C | DMET, SNP6/500K, and Golden Gate |
| 2 | rs1800566 | NQO1 | C/T | T/T | C/T | C/T | DMET, SNP6/500K, and Golden Gate |
| 2 | rs1045642 | ABCB1 | C/C | C/T | C/C | None Available | DMET & SNP6/500K |
| 2 | rs776746 | CYP3A5 | A/G | G/G | A/G | A/G | DMET, SNP6/500K, and Golden Gate |
| 3 | rs2274407 | ABCC4 | G/G | T/G | None Available | None Available | None Concordant |
| 1 | rs2266780 | FMO3 | A/A | None Available | G/A | None Available | None Concordant |
| 4 | rs2266780 | FMO3 | A/A | None Available | G/A | None Available | None Concordant |
| 5 | rs2266780 | FMO3 | A/A | None Available | G/A | None Available | None Concordant |
| 6 | rs1800440 | CYP1B1 | A/G | None Available | G/G | None Available | None Concordant |
| 7 | rs1800440 | CYP1B1 | A/A | None Available | G/A | None Available | None Concordant |