Table 4.
Diagnostic performance of FOB using egg-patent Schistosoma mansoni as a gold standard*
| FOB vs. KK and microscopy | Baseline | 6 months | 12 months |
|---|---|---|---|
| Sensitivity (%) | 36.7 (26.1–48.3) | 47.7 (32.5–63.3) | 30.9 (20.2–43.3) |
| Specificity (%) | 84.2 (79.6–88.1) | 78.4 (73.6–82.7) | 88.5 (84.5–91.8) |
| PPV (%) | 37.7 (26.9–49.4) | 22.3 (14.4–32.1) | 36.8 (24.4–50.7) |
| NPV (%) | 83.6 (79.0–87.6) | 92.0 (88.3–94.9) | 85.5 (81.2–89.2) |
| AUC | 0.60 (0.55–0.66) | 0.63 (0.55–0.71) | 0.60 (0.54–0.66) |
*
FOB = fecal occult blood; CI = confidence interval; KK = Kato-Katz; PPV = positive predictive value; NPV = negative predictive value; AUC = area under the curve (from receiver operating characteristic analysis).