Table 6.
Slopes of SVOL-corrected regional volumes over age for cross-sectional data
| Region | Volume over age
|
Volume over age and sex
|
|||
|---|---|---|---|---|---|
| t | p FDR | best fit | t | p# | |
| Lateral Ventricles | 3.26864 | .00141 * | quadratic | 1.02289 | .30849 |
| Third Ventricle | −2.10049 | .03782 *† | cubic | −.69252 | .49002 |
| Sylvian Fissures | 4.50634 | .00002 * | quadratic | 2.12449 | .03575 |
| Lateral Frontal Cortex | −11.27923 | .00000 * | linear | −1.22095 | .22454 |
| Medial Frontal Cortex | −7.91181 | .00000 * | linear | −.36044 | .71916 |
| Precentral Cortex | −6.83645 | .00000 * | linear | −.30637 | .75986 |
| Postcentral Cortex | −7.02428 | .00000 * | linear | −1.04299 | .29908 |
| Parietal Cortex | −13.14970 | .00000 * | linear | −.36241 | .71770 |
| Temporal Cortex | −10.39591 | .00000 * | linear | −1.34508 | .18118 |
| Calcarine Cortex | −6.45304 | .00000 * | linear | .61709 | .53836 |
| Occipital Cortex | −10.55671 | .00000 * | linear | 1.49778 | .13686 |
| Anterior Cingulate Cortex | −4.85214 | .00000 * | linear | −.96447 | .33678 |
| Posterior Cingulate Cortex | −2.63919 | .00941 * | linear | −1.19576 | .23419 |
| Insula | −5.89171 | .00000 * | linear | −1.67202 | .09717 |
| Precuneus | −4.93880 | .00000 * | linear | −1.19628 | .23399 |
| Thalamus | −10.07233 | .00000 * | linear | −.52865 | .59804 |
| Caudate | −1.78937 | .07610 | linear | .74405 | .45834 |
| Putamen | 2.46346 | .01519 *† | quadratic | .62671 | .53208 |
| Pallidum | −5.02306 | .00000 * | linear | 1.73323 | .08567 |
| Hippocampus | −4.41357 | .00002 * | quadratic | .69544 | .48817 |
| Amygdala | 2.59266 | .01073 *† | cubic | −1.14090 | .25630 |
| Centrum Semiovale | −3.42660 | .00084 * | quadratic | −1.75237 | .08235 |
| Corpus Callosum | −1.15751 | .24937 | linear | −.46150 | .64529 |
*
FDR= false discovery rate, p=.05
*†
lower-order term in unexpected direction
#
None met FDR p = .05