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. Author manuscript; available in PMC: 2012 Dec 6.
Published in final edited form as: Stat Biosci. 2012 Nov 1;4(2):262–281. doi: 10.1007/s12561-012-9061-x

Table 3.

Analysis results for the ARIC study. The Fisher transformation is used for testing ρ, while 50:50 mixture of χ2 distributions is used for testing variances.

Effect Estimate Std. Err p-value Estimate Std. Err p-value
Full Model Reduced Model
Longitudinal measures of SBP
Intercept 1.026 .062 < .001 1.028 .061 < .001
Age 0.338 .044 < .001 0.336 .044 < .001
Male −0.043 .053 .413 −0.039 .053 .461
Total-cholesterol (mg/dL) −0.007 .023 .766 −0.007 .023 .772
Hypertension medication −0.546 .054 < .001 −0.550 .054 < .001
Ever smoker −0.046 .054 .394 −0.056 .052 .288
Diabetes 0.088 .070 .207 0.089 .070 .200
Visit Year 0.014 .004 .001 0.013 .004 .001
σe2
0.500 .016 < .001 0.500 .016 < .001
Recurrent CHD event
Age 0.837 .264 .002 0.506 .150 .001
Male 0.871 .220 < .001 0.795 .187 < .001
Total-cholesterol (mg/dL) 0.195 .109 .073 0.184 .071 .009
Hypertension medication 0.191 .234 .414 0.108 .181 .552
Ever smoker 0.862 .309 .005 0.352 .182 .053
Diabetes 1.843 .253 < .001 1.394 .179 < .001
Terminal event
Age 2.187 .405 < .001
Male 0.611 .364 .093
Total-cholesterol (mg/dL) 0.043 .231 .854
Hypertension medication 0.336 .393 .392
Ever smoker 2.336 .653 < .001
Diabetes 2.671 .374 < .001
φ1 −0.460 .471 .329
φ2 1.910 .317 < .001
Variance components for random effect
σ12
0.331 .024 < .001 0.332 .024 < .001
σ22
3.100 .883 < .001 0.809 .223 < .001
ρ 0.241 .086 .007 0.348 .107 .003