Table 1.
Odorants known to activate dorsal OB in rats and some of their physicochemical properties
Polarity category | Odorant | Abbreviation | P(logKow)* | VP (mmHg) | MV | Density# | Polar surface# | bp (°C)# |
---|---|---|---|---|---|---|---|---|
Highly polar | 2-hexanone | 2hex | 1.24 | 11.60 | 100.2 | 0.81 | 17.1 | 127 |
Polar | Ethyl butyrate | EB | 1.85 | 12.8 | 116.2 | 0.87 | 26.3 | 120 |
Methyl valerate | MV | 1.85 | 19.10 | 116.2 | 0.89 | 26.3 | 126 | |
Nonpolar | Amyl acetate | AA | 2.26 | 5.60 | 130.2 | 0.87 | 26.3 | 142 |
o-tolualdehyde | tolu | 2.26 | 0.36 | 120.2 | 1.04 | 17.1 | 200 | |
Highly nonpolar | Vinyl cyclohexane | VC | 3.95 | 13.40 | 110.2 | 0.80 | 0 | 128 |
*Octanol:water partition coefficient, EPI estimate;