Table 1.

Best fit parameters from nonlinear least squares fits of EC1-dependent cell–cell binding kinetics to Eqn 1

Test cell	Cadherin	Density (#/µm2)	Red cell	Density (#/µm2)	2D affinity (×10−4 µm2)	Off rate (s−1)
MDCK	k9 E-cadherin	17	k9 E-cad.Fc	7	3.6±0.2	1.7±0.3
MDCK	k9 E-cadherin	17	ck N-cad.Fc	20	2.5±0.2	1.5±0.3
MDA-MB-435	hN-cadherin	93	ck N-cad.Fc	32	0.70±0.06	1.9±0.3
MDA-MB-435	hN-cadherin	93	k9 E-cad.Fc	7	1.2±0.2	1.5±0.3
MCF7	hE-cadherin	7	k9 E-cad.Fc	18	4.2±0.2	2.4±0.4
MCF7	hE-cadherin	7	ck N-cad.Fc	37	2.7±0.1	2.2±0.4