Figure 2 .

Su(z)2 is a strong suppressor of the dE2f1-dsRNA phenotypes in the eye. (A) The design of the dominant modifier genetic screen using deficiency lines. (B-D) shows the modification of the dE2f1-dsRNA eye phenotype by Su(z)2 alleles. The eye phenotype of GMR-Gal4, UAS-dE2f1dsRNA#8/+ (B) flies can be strongly suppressed by the Df(2R)Exel6062 line (C, the genotype is w¹¹¹⁸; GMR-Gal4, UAS-dE2f1dsRNA#8/Df(2R)Exel6062; +/+) and a null allele of Su(z)2 (D, the genotype is w¹¹¹⁸; GMR-Gal4, UAS-dE2f1dsRNA#8/Su(z)2^1.b7; +/+). (E) Summary of the genetic interactions between Su(z)2 alleles and dE2f1-dsRNA phenotypes in the eye and wing. The suppressive effect was ranked with scores from 1 to 5, with “1” being the weakest and “5” the strongest. “0” means no genetic interaction. The scale bar in (D) is 200µm.