Table 3. Some of the PcG and TrxG genes dominantly modify the phenotypes caused by varied dE2F1 and RBF1 in the Drosophila eye and wing.
| Mutant Alleles | GMR-Gal4,UAS-dE2f1-dsRNA#10a,b | ptc-Gal4,UAS-dE2f1-dsRNA#3a,b | Act88F-Gal4,UASdE2fa,b | GMR-Gal4,UASdE2f1, UAS-dDpa,b |
|---|---|---|---|---|
| Suppressors | ||||
| Asx1 | Suppression (5) | Suppression (1) | Enhancement (1) | NE |
| effmer4 | Suppression (5) | Suppression (2) | NE | NE |
| E(Pc)84DET66.1 | Suppression (5) | Suppression (1) | NE | NE |
| esc1 | Suppression (4) | NE | ND | ND |
| esc21 | Suppression (5) | Suppression (4) | ND | ND |
| His2AvD810 | Suppression (5) | Suppression (2) | ND | Enhancement (3) |
| His2AvD05146 | Suppression (5) | Suppression (3) | ND | Enhancement (3) |
| KisBG01657 | Suppression (5) | Suppression (2) | NE | NE |
| Pc3 | Suppression (5) | Suppression (5) | ND | Enhancement (4) |
| Pcf01890 | Suppression (5) | Suppression (2) | ND | Enhancement (1) |
| pho1 | Suppression (5) | Suppression (1) | Enhancement (1) | NE |
| ScmD1 | Suppression (5) | Suppression (4) | ND | ND |
| Su(z)21 | Suppression (5) | Suppression (4) | ND | Enhancement (1) |
| Su(z)21.a1 | Suppression (5) | Suppression (5) | NE | NE |
| Su(z)21.b7 | Suppression (5) | Suppression (3) | Enhancement (1) | NE |
| Su(z)2k06344 | Suppression (5) | Suppression (3) | Enhancement (1) | NE |
| Su(z)123 | Suppression (5) | Suppression (2) | NE | NE |
| tara1 | Suppression (5) | Suppression (1) | ND | NE |
| tou2 | Suppression (5) | Suppression (2) | Enhancement | NE |
| brm2 | Suppression (5) | Suppression (2) | NE | NE |
| trxKG08639 | Suppression (5) | Suppression (1) | NE | NE |
| Enhancers | ||||
| E(Pc)w3 | Enhancement (4) | Enhancement (3) | Suppression (1) | ND |
| E(Pc)D4 | Enhancement (5) | Enhancement (5) | Suppression (1) | ND |
| Mi-2j3D4 | Enhancement (4) | Enhancement (1) | Suppression (4) | NE |
| Mi-2EY08138 | Enhancement (5) | Enhancement (1) | ND | ND |
| Su(z)31 | Enhancement (5) | Enhancement (4) | Suppression (1) | ND |
| taraBG01673 | Pupal lethal | Enhancement (4) | Lethal | Lethal |
a
The effects of suppression or enhancement were ranked with scores from 1 to 5, with “1” the weakest and “5” the strongest; NE, no effect; ND, not determined.
b
These crosses were maintained at 25°.
c
These crosses were maintained at 22-23°; see Materials and Methods for the detailed genotypes analyzed.