Table 6. Global burden of rare CNVs in European ASD cases vs. PDx controls.
| Type | Measure | Mean ASD | Mean Controls | Mean ratio ASD/controls | P-value |
|---|---|---|---|---|---|
| All | No. CNV | 2.680942 | 2.565848 | 1.05 | 0.0575976 |
| All | Total CNV size, kb | 124.50 | 112.92 | 1.10 | 0.1804119 |
| All | Total no. genes | 3.850107 | 2.560268 | 1.50 | 0.2345081 |
| Deletions only | No. CNV | 1.958225 | 1.773793 | 1.10 | 0.0046012a |
| Deletions only | Total CNV size, kb | 54.29 | 48.81 | 1.11 | 0.1043462 |
| Deletions only | Total number of genes | 1.741514 | 0.9834483 | 1.77 | 0.0087554a |
| Duplications only | No. CNV | 1.549383 | 1.601266 | 0.97 | 0.7716051 |
| Duplications only | Total CNV size, kb | 101.66 | 96.02 | 1.11 | 0.3778319 |
| Duplications only | Total no. genes | 3.490741 | 2.495253 | 1.40 | 0.8564186 |
a
Significant differences (P ≤ 0.01) are indicated.