Table 2. Effect of sodium selenite (SS, 0.5 mg/kg, i.p.; once daily for 1 week) on oxidative stress markers in rats subjected to a single dose whole-body irradiation (3.2 Gy).
GSH (µmol/g wet tissue) | GPx (U/g wet tissue) | MDA (nmol/g wet tissue) | ||||
Groups | Ovary | Uterus | Ovary | Uterus | Ovary | Uterus |
Control | 4.04±0.48 | 5.01±0.43 | 5.36±1.46 | 2.01±0.23 | 84.8±22.1 | 96.2±10.11 |
IR | 2.47±0.25a | 4.40±0.09a | 3.07±0.78a | 1.24±0.43a | 134.4±15.3a | 275.0±64.55a |
SS | 3.39±0.17b | 5.23±0.41b | 5.89±0.56b | 2.38±0.30b | 82.7±14.3b | 133.8±14.58b |
SS/IR | 3.93±0.64b | 4.94±0.22b | 4.87±0.48b | 2.21±0.30b | 86.4±8.9b | 137.3±24.20b |
Data expressed as Mean ± SD.
a or b: Significantly different from control or radiation group, respectively at P<0.05, using one-way ANOVA followed by Tukey–Kramer as a post-hoc test. Abbreviations: GSH, reduced glutathione; GPx, glutathione peroxidase; MDA, malondialdehyde.