Table 5. Least square means and 95% confidence intervals for the cumulative insomnia symptoms and flow mediated dilation (%).

		Model 1		Model 2		Model 3
Insomnia symptoms	n	Mean	95% CI	Mean	95% CI	Mean	95% CI
Women
0	1,468	5.31	5.08–5.53	5.33	5.06–5.59	5.32	5.05–5.59
1–2	566	5.29	4.93–5.65	5.57	5.12–6.01	5.61	5.15–6.06
3–4	110	5.28	4.46–6.11	5.16	4.17–6.14	5.26	4.26–6.26
P- value for linear trend		0.92		0.72		0.55
P- value for quadratic trend		0.99		0.35		0.35
Men
0	1,345	4.28	4.08–4.49	4.30	4.07–4.52	4.27	4.04–4.50
1–2	380	4.04	3.65–4.42	4.14	3.69–4.58	4.20	3.75–6.66
3–4	58	5.01	4.03–5.99	5.15	4.04–6.26	5.32	4.18–6.46
P- value for linear trend		0.96		0.65		0.39
P- value for quadratic trend		0.06		0.11		0.11

Model 1: Adjusted for age and age squared.

Model 2: Adjusted for age, age squared, marital status, education, smoking, alcohol consumption, physical activity index, BMI, sleep-disordered breathing, snoring.

Model 3: Adjusted for the same variables as in model 2, and depression score and anxiety score.