Table 1. eQTLs overlapping the 1.5 LOD drop region of the PR QTL.
Gene symbol | Refseq ID | Gene name | Max LOD | SNP marker | eQTL cis/trans | Spearmans Corr. to PR rho | pvalue |
Eif4e | NM_007917 | eukaryotic translation initiation factor 4E | 21.58 | rs6407142 | cis | −0.246 | 0.01 |
Gbp1 | NM_010259 | guanylate binding protein 1 | 9.3 | rs6407142 | cis | 0.128 | 0.19 |
Ccbl2 | NM_173763 | cysteine conjugate-beta lyase 2 | 19.77 | rs13477494 | cis | −0.001 | 0.99 |
Cyr61 | NM_010516 | cysteine rich protein 61 | 7.54 | rs13477494 | cis | −0.076 | 0.43 |
Myoz2 | NM_021503 | myozenin 2 | 12.1 | rs13477494 | trans | −0.104 | 0.28 |
Gipc2 | NM_016867 | GIPC PDZ domain containing family, member 2 | 8.05 | rs13477494 | cis | −0.300 | 0.00 |
Abca4 | NM_007378 | ATP-binding cassette, sub-family A (ABC1), member 4 | 12.63 | rs13477494 | trans | 0.105 | 0.28 |
Shmt1 | NM_009171 | serine hydroxymethyltransferase 1 (soluble) | 6.94 | rs13477506 | trans | 0.093 | 0.33 |
Bcl6 | NM_009744 | B-cell leukemia/lymphoma 6 | 9.71 | rs13477506 | trans | −0.218 | 0.02 |
Socs2 | NM_001168655 | suppressor of cytokine signaling 2 | 25.31 | rs13477506 | trans | 0.279 | 0.00 |
Igfals | NM_008340 | insulin-like growth factor binding protein, acid labile subunit | 21.43 | rs13477506 | trans | 0.184 | 0.06 |
Esrrb | NM_001159500 | estrogen related receptor, beta | 7.17 | rs13477506 | trans | 0.102 | 0.29 |
3110057O12RIK | NM_026622 | RIKEN cDNA 3110057O12 gene | 10.34 | rs13477506 | trans | 0.233 | 0.02 |
Tnni3k | NM_177066 | TNNI3 interacting kinase | 56.46 | rs13477506 | cis | 0.263 | 0.01 |
Extl2 | NM_001163514 | exostoses (multiple)-like 2 | 8.01 | rs13477506 | trans | 0.044 | 0.65 |
Gpr177 | NM_026582 | G protein-coupled receptor 177 | 7.93 | CEL.3_159340478 | cis | −0.175 | 0.07 |
Transcripts with a significant linkage overlapping the 1.5 LOD drop region of the PR QTL are listed with their genomic location (build NCBIM37), specific LOD score, marker with the highest LOD score, Spearmans correlation to PR (Rho and uncorrected p value). Transcripts with a significant correlation are marked in bold; Tnni3k is marked in bold and underlined.