Table 2. Sensitivity and specificity of Wb123 IgG and IgG4 LIPS.

Compared to*	Normals	L. loa	O.volvulus	M. perstans	Other Helminths
Sensitivity
IgG	100	100	100	100	100
IgG4	98	98	98	ND	98
Specificity
IgG	100	89	90	100	100
IgG4	100	99	100	ND	100
PPV **
IgG	100	87	90	100	100
IgG4	100	98	100	ND	100
NPV ***
IgG	100	100	100	100	100
IgG4	96	99	98	ND	95

^*Calculations (Sensitivity, Specificity, PPV, NPV) are shown when the positive was defined as sera from proven Wuchereria bancrofti infection and the negative was defined as either normal (Normals), Loa loa-infected (L. loa). Onchocera volvulus-infected (O. volvulus), Mansonella perstans-infected (M. perstans) or infected with soil transmitted helminths (Other Helminths).

ND = not done.

^**Positive Predictive Value.

^***Negative Predictive Value.