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. 2012 Dec 6;6(12):e1936. doi: 10.1371/journal.pntd.0001936

Figure 5. Clofazimine decreases cellular lipid accumulation in M. leprae-infected THP-1 cells.

Figure 5

THP-1 cells were grown on glass coverslips in 24-well plates. Cells with no treatment (A), infected with M. leprae (MOI = 10) (B), and infected with M. leprae (MOI = 10) and treated with clofazimine (2.0 µg/ml) (C) were cultured for 48 h. Oil-red-O staining followed by brief hematoxylin counter staining was performed and observed under a microscope. Representative results from three independent experiments are shown. Bars = 10 µm.